Endogenous isoform-specific CSF-1 signalling determines monocytic AML differentiation therapy response — ASN Events
  1. Schedule
  2. Welcome Reception & Poster Session 1
  3. Endogenous isoform-specific CSF-1 signalling determines monocytic AML differentiation therapy response

Endogenous isoform-specific CSF-1 signalling determines monocytic AML differentiation therapy response (#164)

Samin Iranfar 1 , Jake H Tremewen 1 , Steven Ngo 1 , Johannes Zuber 2 , Ethan P Oxley 1 , Ross A Dickins 1
  1. Australian Centre for Blood Diseases, Monash University, Melbourne, Victoria, Australia
  2. Research Institute of Molecular Pathology, Vienna, Austria
Publish consent withheld
  1. Bonnet, D. & Dick, J. E. Human acute myeloid leukaemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 3, 730-737, doi:10.1038/nm0797-730 (1997).
  2. McKenzie, M. D. et al. Interconversion between Tumorigenic and Differentiated States in Acute Myeloid Leukaemia. Cell Stem Cell 25, 258-272 e259, doi:10.1016/j.stem.2019.07.001 (2019).
  3. Ngo, S. et al. Acute myeloid leukaemia maturation lineage influences residual disease and relapse following differentiation therapy. Nat Commun 12, 6546, doi:10.1038/s41467-021-26849-w (2021).